Research Topics in Optometry

Postgraduate research topics Department of Optometry and Vision Science Postgraduate research topics The following is a list of research topics offered at the doctorate (PhD), masters and honours level.  » Honours  » Masters  » PhD Honours Research Topics| Affiliation – Faculty and Dept| Supervisor/s details| Comparison of animal models of age related nuclear cataract| Optometry and Vision Science| Professor Paul Donaldson p. [email  protected] ac. nz| Mapping antioxidant transporter expression in the front of the eye| Optometry and Vision Science| Dr Julie Lim j. [email  protected] ac. nz| Electron microscopy of protein trafficking in the lens| Optometry and Vision Science| Dr Angus Grey ac. [email  protected] ac. nz| Modelling of lens function  | Optometry and Vision Science| Dr Ehsan Vaghefi e. [email  protected] ac. nz| Exploring neural plasticity in the human visual cortex| Optometry and Vision Science| Dr. Ben Thompson b. [email  protected] ac. nz| Development of aids for colour deficient optometrists| Optometry and Vision Science| Dr. Misha Vorobyev m. [email  protected] ac. nz| Botox: as a tool for eye therapy? | Optometry and Vision Science| Dr Monica Acosta:m. [email  protected] ac. nz| Top Masters Research Topics| Affiliation – Faculty and Dept| Supervisor/s details| Developing functiuonal assays to study membrane protein function in the core of the lens| Optometry and Vision Science| Professor Paul Donaldson p. [email  protected] ac. nz| Chromatic and achromatic vision in reef fish| Optometry and Vision Science| Dr. Misha Vorobyev m. [email  protected] ac. nz| Colour preference in the honeybee| Optometry and Vision Science| Dr. Misha Vorobyev m. [email  protected] ac. nz| Clinical tests for colour vision defects| FoS (Optometry and Vision Science)| Assoc Prof Rob Jacobs r. [email  protected] ac. z| Defocus and visual function| FoS (Optometry and Vision Science)| Assoc Prof Rob Jacobs r. [email  protected] ac. nz| Visual characteristics of NZ population groups| FoS (Optometry and Vision Science)| Assoc Prof Rob Jacobs r. [email  protected] ac. nz| Assessment of refractive error in low vision| FoS (Optometry and Vision Science)| Assoc Prof Rob Jacobs r. [email  protected] ac. nz| Clinical research topics in optometry| FoS (Optometry and Vision Science)| Assoc Prof Rob Jacobs r. [email  protected] ac. nz| How does a cell die? Analysis of photoreceptor cells| FoS (Optometry and Vision Science| Dr Monica Acosta:m. [email  protected] ac. nz| Top PhD Research Topics| Affiliation – Faculty and Dept| Supervisor/s details| Functional characterization of glucose transporters in the lens| Optometry and Vision Science| Professor Paul Donaldson p. [email  protected] ac. nz| Visualization of cell signaling pathways in the ocular lens| Optometry and Vision Science| Professor Paul Donaldson p. [email  protected] ac. nz| Functional characterization of the cystine/glutamate exchanger in the lens: a potential therapy to delay age related nuclear cataract? | Optometry and Vision Science| Dr. Julie Lim j. [email  protected] c. nz| Functional mapping of purinergic signalling pathways in the lens|   Optometry and Vision Science| Professor Paul Donaldson p. [email  protected] ac. nz| Studying membrane protein function in the core of the lens| Optometry and Vision Science| Professor Paul Donaldson p. [email  protected] ac. nz| Antioxidant strategies to prevent age related nuclear cataract| Optometry and Vision Science| Dr Julie Lim j. [email  protected] ac. nz| Investigation of physiological mechanisms that regulate normal eye growth| Optometry & Vision Science| Dr John Phillips j. [email  protected] ac. nz| Investigation of methods for Inhibition of myopia progression in children. | Optometry & Vision Science| Dr John Phillips j. [email  protected] ac. nz| Harnessing neural plasticity for visual rehabilitation| Optometry & Vision Science| Dr. Ben Thompson b. [email  protected] ac. nz| Measuring the human visual cortex response to visual loss with fMRI| Optometry and Vision Science| Dr. Ben Thompson b. [email  protected] ac. nz| The relationship between native New Zealand flowers and vision of native pollinators  |   |   | Colour deficeincy and colour judgement|   | Dr Misha Vorobyev m. [email  protected] ac. z| Visual characteristics of NZ population groups| FoS (Optometry and Vision Science)| Assoc Prof Rob Jacobs r. [email  protected] ac. nz| Defocus and visual function| FoS (Optometry and Vision Science)| Assoc Prof Rob Jacobs r. [email  protected] ac. nz| Clinical tests for colour vision defects. | FoS (Optometry and Vision Science)| Assoc Prof Rob Jacobs r. [ema il  protected] ac. nz| Assessment of refractive error in low vision| FoS (Optometry and Vision Science)| Assoc Prof Rob Jacobs r. [email  protected] ac. nz| Research topics in clinical optometry| FoS (Optometry and Vision Science)| Assoc Prof Rob Jacobs r. [email  protected] ac. nz| Vesicular transport in eye disesases| FoS (Optometry and Vision Science)| Dr. Monica Acostam. [email  protected] ac. nz| Neurochemistry of an animal model of retinal degeneration| FoS (Optometry and Vision Science)| Dr. Monica Acostam. [email  protected] ac. nz | Modelling oxygen / CO2 circulation of the retinal cells| FoS (Optometry and Vision Science)| Dr. Ehsan Vaghefi  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  e. [email  protected] ac. nz| Modelling the electrical stimulation of the retina, using hexagonal electrodes| FoS (Optometry and Vision Science)| Dr. Ehsan Vaghefi e. [email  protected] ac. nz| Creating a full 3D anatomically correct model of the ocular lens| FoS (Optometry and Vision Science)| Professor Paul Donaldsonp. [email  protected] ac. nzDr. Ehsan Vaghefie. [email  protected] ac. nz| Top * FOR * ABOUT * Our department * Our research * Research groups * Publications * Postgraduate research topics * Our courses * Our staff * Careers and opportunities * News and events Apply now! 2012 Handbook Postgraduate Research University of Auckland Clinics SharePrintEmail Copyright  © The University of Auckland A to Z Directory  |  Site map  |  Accessibility  |  Copyright  |  Privacy  |  Disclaimer  |  Feedback on this page | |

Case Brief: London v. Directors of the DeWitt Public Schools

DeWitt Middle School teacher and coach Jeff Rader found Carl Avery and another student engaged in a â€Å"horseplay† in the school cafeteria. Rader asked both boys to leave the cafeteria of which the other student immediately complied. Rader again asked Avery to leave but the boy refused to comply the second time. At this point, Rader began to remove Avery from the cafeteria by force.The boy, however, fought back and slammed the coach into a table. During the encounter, Rader was able to drag the boy on the floor and banged the boy's head against the metal pole outside the cafeteria. They proceeded to the principal's office where each were asked for their version of the story, but Avery struck the hands of the principal in his frustration during the course of the interview, at which point the principal called the police.School authorities recommended for Avery to be expelled, of which DeWitt School District Superintendent Emerson approved. They informed Ms. London, mother of A very, and explained the procedures. A hearing was conducted and the school board decided to expel Avery for the remainder of the school year. Ms. London filed a lawsuit where the District Court granted the defendants' motion for judgement on partial findings, of which Ms.London filed for an appeal on three grounds, that the District Court erred: â€Å"(1) in holding that Rader did not violate Avery's substantive-due-process rights; (2) in holding that there were no procedural-due-process violations in Avery's suspension or in his expulsion; and (3) in not ordering the DeWitt School System to submit a remedial plan concerning discrimination in hiring† (United States Court of Appeals Eighth Circuit 1999). The Eighth Circuit Court of Appeals affirmed with the District Court judgement and dismissed the appeal.They held that Rader could not have violated Avery's substantive-due-process rights as he has asked Avery to leave the cafeteria twice. Although Rader banged Avery's head on a pole, the injury which the boy may have suffered could not have been severe to shock judicial conscience due to the fact that the boy could not even remember which side of his head had been banged. There could also not have been any violation of procedural-due-process as Avery and his mother was appraised of the charges and was given the opportunity to present his side, first in the principal's office, then on the board hearing.The plaintiff has also failed in proving a condition of segregated schooling in accusing the DeWitt School System with discrimination hiring. The decision of the Court of Appeals stressed the importance of effective discipline and order to educational processes. This means that educators have their own discrimination how to discipline students but with restrictions that are provided by law. References United States Court of Appeals Eighth Circuit. (1999). London v. Directors of the Dewitt Public Schools, 194 F. 3d 873, 139.

A promise made to you will not necessarily be enforceable

A promise made to you will not necessarily be enforceable Disclaimer: This work has been submitted by a student. This is not an example of the work produced by our Law Essay Writing Service . You can view samples of our professional work here . A promise made to you will not necessarily be enforceable Consideration means that a promise made to you will not necessarily be enforceable in the courts unless you can establish that you have  given something  for it. Suppose I promise to deliver a ton of gravel to you next week – you get your shovel and barrow ready, and I don’t turn up. I probably would not be liable to you in damages, because you haven’t given anything in return, and merely getting your barrow ready would not be sufficient reliance to make it enforceable. However, if at the time of making the arrangement, you said that you would pay me $10 per ton for the gravel that would be sufficient consideration.  A promise to pay  is sufficient to count as  giving something, even though the promise is not to be put into effect for some time yet.’’ What is Constitute Consideration? Consideration is one of the three essential elements of a valid contract. A promise is made withou t consideration; it does not constitute a valid contract and cannot be enforced in law. Only the contract that has valuable consideration is a valid contract. In a common promise unconfirmed by consideration is not a binding contract. A promise is give without consideration but is intended by the parties to affect an existing contract between them which has been acted upon by one party, and then such promise may be used as a defence by the party to enforce the existing contract. Valuable consideration has been defined as some right, interest, profit or benefit accuring to one party, or some forbearance, detriment, loss or responsibility given, suffered or undertaken by the other at his request. Consideration may be executed or executor, but it may not be past, it need not be adequate, but it must be of some value; and it must move from the promise. In the case of Thomas v Thomas (1842) 114 ER 330, QB, the court held that even though the payment of  £1 a year towards the ground-ven t was a very small sum, it was a valuable consideration and enough to complete the contract. Consideration must be clearly associated with the promise, and past consideration is generally unacceptable. In the case of Re McArdle (1951) 1 All ER 905, CA, the occupants of a house carried out various repairs and improvement, and after the work was complete the beneficial owners of the house promise to pay for this work. They did not pay and the occupants sued. The court of an application held that the consideration for the promise was past and there was no contract. In another way, the occupants failed in the suit because the beneficial owners of the house made the promise after the work was complete. In another case Lampleigh v Braithwait (1615) 80 ER 255, Common Bench said that D asked P to get him a royal pardom. P successful in obtaining to pay him  £100. The majority of breach held that where D makes a request that P does his same service is performed, D promises to pay for it th e promise and the request go together and there is a binding contract. However, the performance of an existing duty cannot constitute consideration. In the case of Collins v Godefroy (1831) 109 ER 1040, KB, D’s subpoena P as a spectator. In court and promise to pay him some fee for his time. D did not pay, in the court held that since the subpoena compulsory a legal duty on P to appear at court, this cannot constitute consideration.

Weber's and Marx Capitalism Essay Example | Topics and Well Written Essays - 1500 words

Weber's and Marx Capitalism - Essay Example This so-called Protestant ethic was the primary impulse for an almost accidental massive social phenomenon that led to the emergence of capitalism. Weber postulates that the unique characteristics of Protestantism and Calvinism were responsible for enabling society to absorb and embrace the capitalistic economic model. In his introduction he writes, A glance at the occupational statistics of any country of mixed religious composition brings to light with remarkable frequency a situation which has several times provoked discussion in the Catholic press and literature, and in Catholic congresses in Germany, namely, the fact that business leaders and owners of capital, as well as the higher grades of skilled labor, and even more the higher technically and commercially trained personnel of modern enterprises, are overwhelmingly Protestant. This is true not only in cases where the difference in religion coincides with one of nationality, and thus of cultural development, as in Eastern Germany between Germans and Poles. The same thing is shown in the figures of religious affiliation almost wherever capitalism, at t he time of its great expansion, has had a free hand to alter the social distribution of the population in accordance with its needs, and to determine its occupational structure. The more freedom it has had, the more clearly is the effect shown. It is true that the greater relative participation of Protestants in the ownership of capital, in management, and the upper ranks of labor in great modern industrial and commercial enterprises, may in part be explained in terms of historical circumstances, which extend far back into the past, and in which religious affiliation is not a cause of the economic conditions, but to a certain extent appears to be a result of them. Participation in the above economic functions usually involves some previous ownership of capital, and generally an expensive education; often both (1). This thesis (convincingly dubbed 'The Weber Thesis'), based on observations as to the distribution of Protestants in the capitalist world, essentially submits the enterprising and comparatively risky Protestant nature (perhaps a product of the then-fresh Protestant revolution) translated from the religious to the economic world, responsible for the development of the capitalistic economic model. This analysis has met with criticism from a number of academic minds. R. H. Tawney, one distinctive and well-known critic, agreed that capitalism and Protestantism were linked; however, in Religion and the Rise of Capitalism Tawney writes that Protestantism adopted the risk-taking, profit-making model from capitalism, and not that capitalism adopted these traits from Protestantism (Tawney, 1926). Sandra Pierotti continues, "The strongest connection that Tawney saw between capitalism and Protestantism was rationality. Protestantism was a revolt against traditionalism and as such advocated rationality as an approach to life and business. Tawney proposed that the rationality inherent in capitalism became a tenet of Protestantism because rationality was diametrically opposed to the traditionalism of Catholicism. Early Protestant leaders recognized that hard work and rational organization of time were capitalist virtues which fit very nicely into the concept of living one's life in the service of God. Tawney saw the capitalist concepts of division of labor and planned accumulation as being reflected in the dogma of Protestantism which urged its followers to use one's calling on earth for the greater glory of God.

Writing a Good Research Paper Example | Topics and Well Written Essays - 1000 words

Writing a Good - Research Paper Example Before carrying out the actual research it is of utmost importance for one to acquire permission from the relevant authorities for them to carry out the research. I the above example, one should get permission from the officer in charge of the specific police department. Describing the purpose of the research paper follows by illustrating and the problem and showing its significance. This is best done by using an interesting example. The problem should be presented in form of a question which is to be answered by the final outcome of the research paper. After describing the purpose of the research paper, it is important to define complex terms, vocabulary, and concepts that will be used throughout the paper since the research may be used by people who are not familiar with such terms. For instance, one can use clearly defined foot notes when giving definitions. This helps to maintain the structure and the flow of the research paper. Before continuing with the research paper, it is ad vised for students to review the scene, topic and problem with their supervisor or teacher by showing them their introduction in order to very if they are on the right course. 2) Literature Review Literature review involves analyzing of secondary sources that touch on the issue being raised by the research paper. When approaching literature review one should use credible academic journals, scholarly article, reports, books, and other research papers that touch on the field of study that one is about to write a research paper on (Online Writing Lab 2004). There is no one definite way of carrying out literature review when writing a research paper. It depend on the referencing style n which on is using that is American Psychology Association... Writing a Good Research Paper In the field of psychology, trends, theories and approaches have changed and new ones emerged from time to time. In fact, new approaches to various issues in psychology have emerged in almost every decade. This being so, there has been the need for scholars and professionals in the field to undertake research on the ground in order for them to identify problems or test whether these new approaches really work. As a result this has created the crucial need for research papers in the field of psychology. This paper will identify and discuss the key elements of a good research paper which are introduction, literature review, hypothesis, methodologies, results, discussion, conclusion, and references. It will also discuss further on the process of writing a god research paper. 1) Introduction When writing a research paper, one should start of by generally describing and introducing the topic. This should be done by establishing how the topics in question fit and relates to the field of st udy. For instance, if one is intending to write a research paper on the effects of substance and drug abuse among law enforcement personnel, then one should explain what is drug and substance abuse and how it is related with law enforcement. It is important to understand that a research paper is not an essay. Hence, the given format must be followed in order for one to illustrate the research undertaken for others to understand and comprehend.

Shakespeare's life Research Paper Example | Topics and Well Written Essays - 1500 words

Shakespeare's life - Research Paper Example Speaking about the personal history of the Shakespeare himself, we cannot state the precise date of his birth, because only according to the information from the church archives we can know that Shakespeare was baptized on April 26, 1564. He lived in Stratford-upon-Avon. Some details about the origin of legendary playwright we can take from his plays, sonnets, and other poems, however, more light can shed official documentation. However, they provide only very brief sketches of the important events of the Shakespeare’s life. From the official documents comes the information that the Shakespeare was baptized at the Holy Trinity Church in Stratford-upon-Avon. From this moment many people consider the beginning of the Shakespeare life. On November 28, 1582, in Worcester, in Canterbury Province, William Shakespeare married Anne Hathaway. Hathaway was from Shottery, it was small village a mile west of Stratford. William was 18 and Anne was 26, and, she was pregnant. Their first child, a daughter they named Susanna, was born on May 26, 1583. Then, after two years they had twins, Hamnet and Judith. However, Hamnet died of unknown causes when she was eleven. Then the history of records ends and seven years considered to be the â€Å"lost years†. These years are undocumented and there are much information from various sources regarding this hidden period of time. Some of them tell that Shakespeare has gone into hiding from the local landlord. Another possibility that Shakespeare could work as an assistant to the schoolmaster of the Lancashire.

Write a reflective learning journal Essay Example | Topics and Well Written Essays - 1000 words - 1

Write a reflective learning journal - Essay Example Whilst the slowdown of last year can be expected to influence the luxury sales growth to raise upto 2.5% for the Chinese consumers, many insignificant players are however predicting the sales growth to increase by â€Å"double-digit rates†. Organizations have now decided to exploit this prevailing trend in China to the fullest and niche brand fashion, clothing and beauty retailers like Lane Crawford, Galeries Lafayette and 10 Corso Como have started running their outlets recently in the locations of the mainland China. The minor boutique brands are on the growing phase in both the e-commerce and the brick-and-mortar domains. The online outlets for individuality such as new social media websites and fashion blogs are reshaping the tastes of the Chinese consumers in the coming years and the retailers are presenting more personalized and special-edition products, as well as  Ã¢â‚¬Å"VIP  services†, to the Chinese market (Doran, 2014). These changes are the result of incr eased penetration of online shopping trends and enhanced visits of the Chinese customers to the foreign nations. Thus it can be stated that in the recent months, the changes in the taste and preference of the Chinese customers has affected the fashion and clothing trends of the population and as a result more and more foreign brands are entering the nation to serve those transformed fashion patterns. PETA  has recently acknowledged the fashion brands that are "kind to animals" in its 2nd yearly PETA-Approved Vegan Fashion Awards. The long time promoter  of cruelty-free fashion, Stella McCartney  is pleased to be counted among the â€Å"long-time the line-up†. The designer stated to Vogue, "PETA are always willing to put their necks on the line and always with a provocative sense of humor† (Miligan, 2014). McCartney is strictly against the usage of animal skin and fur in apparel designing. She herself never used animal skins in her accessory or clothing

Learning of Mathematics in Secondary Schools Essay

Learning of Mathematics in Secondary Schools - Essay Example Today, in whatever domain of work we look into, we always find the impact of technology continuously revolutionizing those fields and industries. The education industry is no exception. When looking deep into various disciplines of studies to analyze the actualized as well as potential impact of technology, we come across the fact that the understanding of the subjects which are very conceptual in nature, increases many folds. Mathematics is one of them. Furthermore, especially in secondary classes in Singapore, when the course of mathematics starts to get more conceptual and complex, it becomes essential to let the students visualize various concepts using multimedia, which would otherwise be impossible to demonstrate. Thus this study aims to analyze the impact of use of Information and Communication Technology in the enhancement of learning of Mathematics in the secondary schools of Singapore, particularly in the assessment aspect of teaching. Information Communication Technology i s too broad area to be analyzed as a whole, thus we would restrict ourselves to the impact of multimedia technologies only. This specification leads us to our research question, that is, This literature review is aimed to look at the work relevant to the issue that has already been done. Thus, first of all we would start with defining the term multimedia, without as well as within the context of Information Communication Technology. Moving further, we will analyze the various researches done on the issue of teaching methodologies and its relation with technologies. The term 'relation' here includes the advent, the nature and level of integration of technology and teaching over time and impact. Moving further, we would review the literature on how the multimedia technologies can facilitate the teaching of mathematics. Lastly we would try to analyze that keeping in view the existing literature, what is the need of the proposed research. It is important to be clear in very beginning that what perspective of multimedia we are considering, in order to avoid any ambiguity. In a literal sense, the word multi means many and media means the plurality of mediums, the way of delivering some thing. The type of information that is considered as part of media are diversified, it includes, text, graphics, animations, sounds and video clips. The list is not exhaustive; with the evolution of technology new types of media keep on being added. For example, initially only text was the media to be used, then graphics and then sounds, animations and clips and so on. When we speak of the term multimedia in terms of information and communication technology, it has been defined as Multimedia is communication that uses any combination of different media; it may or may not involve computers. Multimedia may include text, spoken audio, music, images, animation, and video. . Multimedia programs are often interactive and include games, sales presentations, encyclopedias, and more. From this definition we can infer some

Emergency Services Management - ManMade Disasters - Media Essay

Emergency Services Management - ManMade Disasters - Media - Essay Example Smoke and soot content in air could rapidly increase 1 to 2 hours prior to the fire reaching the perimeter of our town. 3. As a safety measure, I have ordered the evacuation initially of the western suburbs of Everyville consisting of the areas west of the canal. Evacuation of additional areas may become necessary as we track the advancement of the wildfire. The areas identified for immediate evacuation are shown in the attached map. 4. The evacuation will begin in approximately 1 hour from now and should be completed in a maximum of 2 hours. Police and fire service personnel are being deployed in the area to assist in the evacuation. I request all citizens to help these civic employees, who are putting their lives at risk, to do their jobs effectively. Failure to comply with instructions from police or fire services personnel would be treated as a criminal offence. 5. Carry only the minimum essentials with you when you evacuate your home. These essentials are shown in the simple chart below. In addition carry sleeping bags and change of clothing for each family member and some food and drinking water to supplement what is being arranged at the refuge centers. . You can use your own cars or trucks to move to the refuge areas or use the transport vehicles that have been arranged by the civic authorities. The police and fire service personnel would provide guidance. 6. The refuge areas identified in the town of Everyville are the Civic Center, The Church of St. Andrews, and the High School. The location of these refuge areas are shown on the map released with this statement. Volunteers have been positioned at each of these buildings to assign spaces and to help people settle in. Some arrangements for food and water are also being made. Doctors and nurses from the town hospital will be available to provide medical assistance if needed (CWPP, 2008). 7. Before you

English-language films Essay Example for Free

English-language films Essay Working as a congressional page, I was given the ability to manage my academic success through my own initiative. Dealing with independence was a revealing experience for me, giving me new responsibilities and shaping my work ethics. I didn’t have my parents, now 5,000 miles away, to urge me to finish my homework or to nag about my less than perfect grades, and I couldn’t depend on the support of the teachers or counselor that I knew so well to look after my academic well-being. There was a realization that I was alone in my struggle to succeed and become a responsible student. This independence allowed me to take the situation into my own hands and to work out my own problems, knowing I was the dictator of my consequences and decisions. In this situation, I learned how to set my priorities, a skill that has taken me a step toward preparing for college. Knowing that education would provide the foundation for my future in college and beyond, I placed it at the top of my values, so even in the excitement of new friends and complete independence, I had to maintain it as my first priority. Though it proved difficult to discipline myself without support and accountability alone, I managed to succeed. I’d invite friends over to my room to study, and it eventually became a custom to for us hold study sessions in my room every Monday night and before test days. The entire night was devoted to completing our assignments, studying for exams, and tutoring each other. After the strenuous study session, we’d reward ourselves with a movie and light conversations. These study sessions were an efficient way in which I could balance two of my important priorities, friends and academics. Living on my own and balancing a hectic load of school, work, and dorm life, I gained insight in effectively managing my own time, which was essential in preparing myself for academic success. It wasn’t a rare occurrence for Congress to stay into the thick hours of the morning, debating over a controversial issue, such as the budget or immigration. During these nights, I was required to wait on congressman on the Floor and carry out errands late into the night. Working late did not give us amnesty from the school’s assignments, so we had to make the most use of whatever time we had. Working as a page obviously cut into the precious time I had to concentrate on my school work, forcing me to partition my time wisely. It became an unsaid rule for me to sign myself into an hour of study hall every week night, so that I wouldn’t be distracted by roommates or requests to go out. I had an excuse to delay my friends’ invitations to the movies or to the mall until I felt confident I could do my best on the pre-calculus or history test we would have on Friday. With my packed schedule, I spent my time wisely to get the most out of my experience in Washington, while maintaining my grades and academics. The independence that I was fortunate enough to experience for the first time exposed me to responsibilities has helped me to prepare for college. It has disciplined me to set my priorities and manage my time to be the most effective student possible. Like a young eagle learning to fly, I learned to steer myself in the right direction. And so, I landed a more prepared and experienced person.

Tissue Types in the Human Body

Tissue Types in the Human Body A tissue is a large collection of cells that carry out a specific function together. Organisms are made up of groups of different tissues. There are four main types of tissues, these are: Epithelial tissue, Muscle tissue, Connective tissue and Nervous tissue. These four tissue types each have their own specific function vital the human body. Because of this, each type of tissue contain cells with specific organelles appropriate to the tissues function. The addition, removal, or adaption of cell features can impact greatly on a tissue, giving it the properties it needs in order to accomplish its role in the body. Epithelial tissue covers the whole of the bodys surface. Epithelial cells are packed closely together in one or more layers. Epithelial tissue specialises in covering the bodys external and internal surfaces. The epithelial tissue located in the bodys interior is known as endothelium. Epithelial tissue can be split into two groups depending on the number of layers its composed of. When the epithelial tissue is only one cell thick its known as simple epithelium. However if the epithelium tissues is two or more cells thick, such as the skin, its known as stratified epithelium.   The main purpose of the epithelial cell is to protect the surfaces it covers, in some cases however specialised epithelial tissues are able to take part in absorption, excretion, secretion, diffusion, and cleaning. Epithelial tissue has the ability to repair itself this is due to the basement membrane which is a selectively permeable membrane. The epithelial tissues ability to repair itself is very useful as it comes under constant wear and tear because of its protective function. The repair process requires a lot of protein to be produced, therefore a large rough endoplasmic reticulum is needed in order to synthesise large amounts of protein. The top layer of cells within the epithelial tissue is often keratinised, making it stronger and more resistant to damage. The nucleus within the epithelial tissue cells are able to change shape depending on the overall shape the cell structure will take on. The nucleus does this in order for the epithelial cells to fit closely together. Epithelial cells can also contain appendages known as cilia, depending on the tissues function. Cilia are often found in epithelial tissue located in areas such as the throat. Cilia waft the mucus with in the throat, reducing restriction and build up. Muscle tissue There are three types of muscle tissue: Smooth muscle tissue, skeletal muscle tissue and cardiac (heart) muscle tissue. The main function of muscle tissue is to create movement of, and in the body. A large of amount of energy is needed within the muscle tissue due to its function, movement. This energy comes from ATP which is made within the tissues cells. Because of this muscle cells contain a vast amount of mitochondria which is responsible for creating ATP. The large number of mitochondria means vast amounts of ATP can be produced and then converted into kinetic energy needed for the muscle movement. Muscle tissues need to be sturdy and resilient due to the amount and type of movement carried out by the cell. This is accomplished by the cell membranes of the muscle cells, known as the sarcolemma. Smooth muscle tissue controls slow, involuntary movements. Skeletal muscle tissue is responsible for the movement of the various bones of the skeleton. Cardiac muscle tissue is found only on the hearts walls, it shows characteristics of both smooth muscle tissue and skeletal muscle tissue. Cardiac muscle tissue is responsible for the contraction of the atria and vesicles of the hear t. Muscle tissue is strong due to its outer layer of collagen fibre, which covers the inner layer known as the plasma membrane. Muscle tissue needs to be able to contract to perform its function. To do this calcium is needed. The calcium needs to be stored within the cell and transferred when needed. The calcium needed is packaged and kept in the cells sarcoplasmic reticulum this is an organelle similar to the SER. The cytoplasm of muscle tissues, called sarcolemma, is unique because it contains large particles of glycogen (storage of energy) and has a high concentration of calcium. This enables the muscle to contract efficiently Connective Tissue Connective tissue can be found within and throughout the human body, taking on many forms varying on its function. Whether its tendons and bones, or blood and skin. The main function of connective tissue is to support the human body and connect together different types of tissues. Connective tissue usually has scattered cells throughout an extracellular matrix. Connective tissues are composed of three main types of cells: Fibroblasts, Macrophages, and Mast cells. Fibroblasts are responsible for creating an extracellular matrix within the tissue, this gives the connective tissue elasticity needed so the tissue can stretch and then return to its original shape when needed. Collagen and proteins mostly make up the matrix providing strength to the tissues as well as flexibility. Macrophages are cells that come from blood cells and clean any Foreign particles present through the process of phagocytosis. The final primary cell type is the Mast cell. The mast cell communicates with the bodys blood chemically, instructing it when to clot its blood, or inflame particular tissues. Mast cells provide the connective tissues with vital reparative properties that are needs when damage takes place. Nervous tissue Nervous tissues are built of nerve cells. The main function of the nervous tissue is relaying electrical impulses from one are in the body to another, collecting, sending and managing information from area to area. The nervous tissue is made up of special nerve cells called neurones. Neurones transmit impulses at a very fast rate and are easily stimulated. The three main neurone types are: Sensory neurone, Motor neurone and connector neurones. Nervous cells are built of a standard cell body, contain cell organelles such as; nucleus, nucleolus, mitochondria, ribosomes, cell membrane and cytoplasm. The Golgi apparatus however is slightly different, not only can it process and package proteins it can also process and package neurotransmitters. At either end of the cell body are protrusions. One of these protrusions is known as the axon, this is a nerve fibre that attaches to the soma, carrying impulses away from it. The axon has a specially adapted membrane that can connect with the membrane of a targeted cell, letting impulses be carried into it. These connections are known as synapses. The dendrite which stems from the other end of the soma, works differently to the axon, picking up impulses from surrounding neurones and transmitting it to its own soma. A material made of protein and fat known as the myelin sheath, acts as a sheath around the axon of a nerve cell. Its primary functions are to protect and insulate the nerve fibre, stopping impulses leaving he cell from incorrect areas, and also increase the speed of the impulses. Ranvier are regular gaps that are located along the sheath, these let nutrients and waste enter and leave the neurone. They also let the impulses move along the neurone itself. These features are what give the nervous tissue the ability to send information to different areas of the body and coordinate bodily functions allowing the body to carry out its intended purpose

Saloon Culture Essay -- essays research papers

Saloon Culture   Ã‚  Ã‚  Ã‚  Ã‚  Royal Melendy writes about a rising social culture taking place at the turn of the twentieth century. He depicts this culture as the ambiance emitted in early Chicago saloons. â€Å"Saloons served many roles for the working-class during this period of American history, and were labeled as the poor man’s social clubs† (summary of saloon culture, pg. 76).   Ã‚  Ã‚  Ã‚  Ã‚  Saloons were described as part of the neighborhood. An institution recognized and familiar to its people. Many laws restricted their services; however, they continued to exist. The article talks about two types of saloons. The first being the more upscale in downtown districts. These would close around midnight not in accordance to law, but demand. The other type Melendy calls â€Å"saloons [of] workingmen’s districts† (Melendy, pg. 77). He illustrates these clubs as home away from home. They supplied the basis of food supply for those whose home was in the street or for those residents of cheap lodging establishments. It is even stated that many saloons provided free lunches.   Ã‚  Ã‚  Ã‚  Ã‚  The article discusses the need for these early Chicago saloons as a neighborhood commune for those men who labor long hours only to come home to poverty and despair of a desolate household. Melendy focuses on the mental, physiological, and moral nature of these workingmen. He points out that this saloon culture allows it’s patrons to develop these traits by interacting with their peers—others facing the same despair. These establishments are described as the â€Å"workingman’s school. He is both scholar and teacher† (Melendy pg. 78). Patrons gather at the bar, around tables and in the next room amongst games of pool, cards, and darts to discuss political and social problems, sporting news, and other neighborhood gossip. Here men, native and immigrant, exchange opinions and views of patriotism, brotherhood, and lessons in civil government. Melendy describes this atmosphere as cosmopolitan, and articulates that these businesses advertise this issue in their names. For example one of the downtown saloons was entitled â€Å"Everybody’s Exchange.† The saloon’s customers experienced a buffet of nationalities upon which was not so for those of poverty in previous decades. Saloons also served as disguises of corruption as Melendy illustrates by declaring â€Å"... ... Melendy’s discussion are lightly touched on in the excerpt. The article does explain how some patrons abused alcohol and would â€Å"revel in drunkenness and shame,† (Melendy, pg. 76) and even how the saloon wrecked their life. It also expresses the fact that some saloons would display nudeness and play on human lust in order to boost liquor sales. Finally, Melendy in his last sentence of the excerpt states â€Å"the youths are here [the saloon] corrupted is too well known†¦Ã¢â‚¬  (Melendy, pg. 79). Courtesy of the Chicago Historical Society. Available at: http://homicide.northwestern.edu/timeline/1905/large/29.jpg References A Millennium Biography, Chicago in 1900. (October 1999). Available at: http://www.chipublib.org/004chicago/1900/fun.html Melendy, Royal. â€Å"The Saloon in Chicago,† The American Journal of Sociology, 6 (November 1900): 289-306. Above references with page numbers note an excerpt of this article as published in For the Record: A Documentary History of America from Reconstruction through Contemporary Times. Edited by David E. Shi and Holly A. Mayer. Other references denote the full length article available at:   Ã‚  Ã‚  Ã‚  Ã‚  http://historymatters.gmu.edu/d/5765/ Saloon Culture Essay -- essays research papers Saloon Culture   Ã‚  Ã‚  Ã‚  Ã‚  Royal Melendy writes about a rising social culture taking place at the turn of the twentieth century. He depicts this culture as the ambiance emitted in early Chicago saloons. â€Å"Saloons served many roles for the working-class during this period of American history, and were labeled as the poor man’s social clubs† (summary of saloon culture, pg. 76).   Ã‚  Ã‚  Ã‚  Ã‚  Saloons were described as part of the neighborhood. An institution recognized and familiar to its people. Many laws restricted their services; however, they continued to exist. The article talks about two types of saloons. The first being the more upscale in downtown districts. These would close around midnight not in accordance to law, but demand. The other type Melendy calls â€Å"saloons [of] workingmen’s districts† (Melendy, pg. 77). He illustrates these clubs as home away from home. They supplied the basis of food supply for those whose home was in the street or for those residents of cheap lodging establishments. It is even stated that many saloons provided free lunches.   Ã‚  Ã‚  Ã‚  Ã‚  The article discusses the need for these early Chicago saloons as a neighborhood commune for those men who labor long hours only to come home to poverty and despair of a desolate household. Melendy focuses on the mental, physiological, and moral nature of these workingmen. He points out that this saloon culture allows it’s patrons to develop these traits by interacting with their peers—others facing the same despair. These establishments are described as the â€Å"workingman’s school. He is both scholar and teacher† (Melendy pg. 78). Patrons gather at the bar, around tables and in the next room amongst games of pool, cards, and darts to discuss political and social problems, sporting news, and other neighborhood gossip. Here men, native and immigrant, exchange opinions and views of patriotism, brotherhood, and lessons in civil government. Melendy describes this atmosphere as cosmopolitan, and articulates that these businesses advertise this issue in their names. For example one of the downtown saloons was entitled â€Å"Everybody’s Exchange.† The saloon’s customers experienced a buffet of nationalities upon which was not so for those of poverty in previous decades. Saloons also served as disguises of corruption as Melendy illustrates by declaring â€Å"... ... Melendy’s discussion are lightly touched on in the excerpt. The article does explain how some patrons abused alcohol and would â€Å"revel in drunkenness and shame,† (Melendy, pg. 76) and even how the saloon wrecked their life. It also expresses the fact that some saloons would display nudeness and play on human lust in order to boost liquor sales. Finally, Melendy in his last sentence of the excerpt states â€Å"the youths are here [the saloon] corrupted is too well known†¦Ã¢â‚¬  (Melendy, pg. 79). Courtesy of the Chicago Historical Society. Available at: http://homicide.northwestern.edu/timeline/1905/large/29.jpg References A Millennium Biography, Chicago in 1900. (October 1999). Available at: http://www.chipublib.org/004chicago/1900/fun.html Melendy, Royal. â€Å"The Saloon in Chicago,† The American Journal of Sociology, 6 (November 1900): 289-306. Above references with page numbers note an excerpt of this article as published in For the Record: A Documentary History of America from Reconstruction through Contemporary Times. Edited by David E. Shi and Holly A. Mayer. Other references denote the full length article available at:   Ã‚  Ã‚  Ã‚  Ã‚  http://historymatters.gmu.edu/d/5765/

How does J.D Salinger use the character of Holden Caulfield to explore :: English Literature

How does J.D Salinger use the character of Holden Caulfield to explore the issues related to growing up? ‘The Catcher in the Rye’ was written in the late 1940’s and first published in a magazine in 1947. The novel is like a bildungsroman but only consists of two and a half days in the life of a 17 year old boy called Holden Caulfield, although he argues that the book is not about his â€Å"lousy childhood†. Holden seems to be very conscious of this and doesn’t want it to be â€Å"all that David Copperfield kind of crap†. Nevertheless the book is an insight into a young man’s mind. Salinger creates Holden Caulfield’s idiolect with all the colloquialisms and swearing, which resulted in the book being banned in many states of America. Holden is very open and does not refrain from sharing some of his views on society and the war. At the time of publishing, America was experiencing very rich, prosperous, affluent years. Hollywood was the worlds best film industry and something America was very proud of and enjoyed, â€Å"Everybody was on their way to the movies† but Holden â€Å"couldn’t stand looking at them†, this was a big dig at American society and became very controversial. Holden doesn’t hold back his political views either, â€Å"I’m sort of glad they’ve got the atomic bomb invented. If there’s another war, I’m going to sit right the hell on top of it†. Due to the contextual time of post WW2 this was deeply shocking and disturbed many people, the atomic bomb had killed millions of innocent people and thousands had relatives lost in the war. At this time America was very anti-communism but Holden hints anti-capitalist views, â€Å"Goddamn money. It always ends up making you feel blue as hell†, and he often wears a â€Å"red hunting hat† which could have easily symbolized a communist. This was also a contributing factor to the shock this gave American society. However these are just the views of a teenager and all is part of J.D Salinger exploring the confused, rebellious thoughts of someone growing up. Salinger explores the issues of growing up in many different ways. Most of them contradict themselves at some point as well, portraying the confusion and unsettled mind of an adolescence. One of these main issues is Holden’s longing to gain independence. This is seen from early on in the book and is carried on throughout. The first main example of Holden wanting to move freely with independence is when he decides he’d â€Å"get the hell out of Pency...not wait till Wednesday† when he is supposed to break up from his boarding school.

Free Essays - The Hazards of Moviegoing :: Example Personal Narratives

The Hazards of Moviegoing    I am a movie fanatic. When friends want to know what picture won the Oscar in 1980 or who played the police chief in Jaws, they ask me. My friends, though, have stopped asking me if I want to go out to the movies. The problems in getting to the theater, the theater itself, and the behavior of some patrons are all reasons why I often wait for a movie to show up on TV.    First of all, just getting to the theater presents difficulties. Leaving a home equipped with a TV and a video recorder isn't an attractive idea on a humid, cold, or rainy night. Even if the weather cooperates, there is still a thirty-minute drive to the theater down a congested highway, followed by the hassle of looking for a parking space. And then there are the lines. After hooking yourself to the end of a human chain, you worry about whether there will be enough tickets, whether you will get seats together, and whether many people will sneak into the line ahead of you.    Once you have made it to the box office and gotten your tickets, you are confronted with the problems of the theater itself. If you are in one of the run-down older theaters, you must adjust to the musty smell of seldom-cleaned carpets. Escaped springs lurk in the faded plush or cracked leather seats, and half the seats you sit in seem loose or tilted so that you sit at a strange angle. The newer twin and quad theaters offer their own problems. Sitting in an area only one-quarter the size of a regular theater, moviegoers often have to put up with the sound of the movie next door. This is especially jarring when the other movie involves racing cars or a karate war and you are trying to enjoy a quiet love story. And whether the theater is old or new, it will have floors that seem to be coated with rubber cement. By the end of a movie, shoes almost have to be pried off the floor because they have become sealed to a deadly compound of spilled soda, hardening bubble gum, and c rushed Ju-Jubes.

How to Deal with Disagreements Between Children and Young People Essay

Dealing with conflicts with children can be challenging. Young children get very emotional and are often crying. Especially children in Infants years, the smallest thing can cause a disagreement, usually in the playground over toys. I find the best way to deal with conflicts is to be calm and get each child to explain what happened, this shows you are not taking sides and you are listening to both, explain the difference in right and wrong. Try to make them understand if they were put in the same position, how they would feel and get them to apologise. Also, younger children, especially those who may be an only child find it harder to share. This is another issue affecting disagreements in this age group. For example, during art class, sharing colours, some children don’t have the patience to wait for their turn; this causes little conflicts amongst children. So I try to explain to them that they should be patient, be considerate of others and wait for their turn. Whereas with young people you need to have a different strategy in order to deal with disagreements. This age group are strong willed and most will have their own views and ideas. They are more independent and have their individual personalities hence will clash more. They should be encouraged to discuss the issue and come to a mutual agreement. Learning to accept others views and opinions and to respect this. Adults should give young people the opportunity to resolves issues themselves and intervene only when needed. I feel when dealing with young people, you need to be able to listen to them, let them explain the issue before jumping in giving them your view. If the matter is discussed, they will realise for themselves what is the right answer.

Reluctant Users Slow O Take Up Videoconferencing Essay

The public relations executive was enthusiastic on the phone. The IT company he represented had started installing green data centres and energy-efficient computers. Would I like to fly to California to see for myself? That would be a 2500 mile round trip from my home in Midwestern Canada. According to the online calculator from Terapass, the trip would release 1,1232 pounds(about 500 kilos) of CO2 into the atmosphere. ‘If you’re really into green technology, couldn’t we do a videoconferencing instead? ’ I asked. ’Sure,’ said the PR person. We are totally into green issues’. He promised to arrange it. Months laters, nothing had happend. The high-tech industry is quick to praise the benefits of flexible communication, but videoconferencing is one area where things have failed to live up to the hype. ‘Videoconferencing has not significantly displaced travel,’ say Frank Modruson, CIO for global technology consulting firm Accenture. As the IT sector continues to push its green values, this mismatch between rhetoric and reality is becoming harder to ignore. So why are relatively few people using videoconferencing? Andrew Davis, managing partner at online collaboration market research firm Wainhouse, says the technology is let down by usability. For many peple, videoconferences are just too difficult to set up. This is why Nortel is emphasizing the services side. ‘The barrier isn’t the technology. It’s the services around that technology,’ says Dean Fernades, the company’s General Manager of Network Services. Nortel is one of several companies getting into a relatively new segment of the videoconferencing market called telepresence. Specially equipped rooms enabled people to appear as if they are sitting across the table, with life-size video representations of remote colleagues in high-definition video. Customers pay to use Nortel’s facilities, which can also handle video filming, enabling the room to double as a production facility for corporate TV, for example. Nortel will also handle post-production tasks such as editing. Accenture, on the other hand, opted for the capital investment route. Mr Modruson said it is installing rooms in Chicago and Frankurt, and hopes to roll out another 11 cities in the next few months.

Small Towns Big City

Costumes Bring out Different Personalities Pulling up in the parking lot there are small groups of people crowded around getting out of their cars and preparing to enter the building, there is laughter and talking throughout the parking lot leading up to the building. Everyone is dressed in costumes for the theme of the party; there are mummies, zombies, cartoon characters, fairies, devils, musicians, super Heroes, cowboys and cowgirls, and many more. Everyone wearing a costume seems to present a more outgoing and somewhat â€Å"false† personality relevant to the character or thing that their costume is portraying.As we walk closer to the entrance from the parking lot you can hear the music, and the noise of the people inside. The music is loud and draws a crowd towards the doors. When we arrive at the entrance to the building there is a lady about five feet five inches tall with light brown shoulder length hair wearing a cowgirl outfit, standing behind a booth, checking Ident ification to ensure everyone who enters is at least twenty one years of age, and also collecting the entrance fee from each person. She’s talking with a fake country accent that helps add character to her costume.Her personality is bubbly and welcoming; it sets the tone for what the atmosphere is inside the building. There is another person at the entrance, a man standing beside her he is tall about six foot five or so, he has short brown hair and is wearing a uniform shirt instead of a costume. His personality is more calm and natural; I feel that this is because he is not in a costume so he doesn’t have the same ramp up as the others who are in costume have. He checks everyone’s bags for weapons, alcohol, and anything that would not be permitted inside the building.He then places a paper bracelet around each person wrist to identify that they have been checked through security, and are permitted to enter the building, this also helps the bartenders identify th at the person they might be serving alcohol to have been verified as over the age of twenty one. When we walk in the front door the noise of laughing, talking and the music has gotten much louder, it is now clear what the atmosphere in the building is, there are people everywhere, talking, drinking, and having a good time, it seems fun and relax, entertainment is everywhere.No matter what direction you turn there are so many different smells, but with the huge crowed of people the strongest of all the smells would by far be the body odor. Straight ahead as soon as you walk in the door there is a bar where a bar tendered dressed in a devil costume stands taking orders and making drinks, she seems busy and more mute then the rest of the employees, but every once in awhile she will scowl in a fun way at someone in character to her costume.There is a large line of people surrounding the bar waiting for their turn they are all laughing and some are even in a playful mood using props to t heir costumes as weapons to battle with each other. To the left is a long table of people, a dance floor, and a DJ station. Looking to the right there is more small grouped tables, restrooms, and a door to an outside area where people are smoking and talking. There is a group of people standing outside dressed as the ghost buster crew, they are all acting out scenes from the movie, they are sure to stay in full character through the entire scene.Their enthusiasm is entertaining to say the least, and it draws a crowd of people. Others start to join their lead, there is a small group of pirates that are also sward fighting and talking in accents that suggest their characters. The outside atmosphere is more playful then inside and is also a little quieter. Overall everyone is having a good time and the theme of the party is in honor of the holiday Halloween.There is costume contest that everyone was encouraged to enter, it seems to ramp up the excitement throughout the building, everyo ne begins to gather around the stage. They had everyone who entered the costume contest line up on stage one by one. The costumes were judged by the crowed in a scale of how loud their yelling was. As each person was presented in the line of contestants they acted in a way to present the character of their costumes. There was a woman dressed up as a lion tamer, and another woman with her dressed as a lion.They acted out a scene when it was their turn on stage. The tamer attempted to tame the wild lion while the lion persistently tried to attack the tamer. As the night goes on the atmosphere changes, everyone has obviously had a lot more to drink and the levels of intelligence have diminished. As I look to my left by the dance floor I see a fight between two girls, there are shoes flying, and a crowd of people quickly gathering to get in on the action. This is now becoming an atmosphere that I may not want to be in for much longer.Although the festivities are quiet entertaining and a drenaline is pumping with every move from the dance floor it is now clear that the night is almost over. As the bouncers approach the crowed they move through aggressively to break up the fight, and sort out what has happened. I watch intently to see the damages that are done its almost sad how entertaining this has become. Once the fight has been broken up, those involved in the fight, and the bouncers all leave out of the building, the party then goes on.The DJ makes an announcement that this will be the last song and the party will soon end. As the last song comes to an end the crowd of people being to leave out the front door. Everyone is still playful and maintain their characters as they gather around their vehicles and begin to reverse the entire process. Overall the night was entertaining to say the least the costumes created an atmosphere that was out of the normal and would most likely not have existed if it wasn’t for the costume and the theme of the party. Clear a nd engaging introduction that clearly states a strong thesis: 14/20 While engaging and full of detail, there is no clear thesis or map. Something like, â€Å"this was a great party because of the atmosphere, the costumes, and the mood† would have worked. * Clearly established supporting details, in the form of observations, that support your thesis: 15/20 There are lots of supporting details, but because the framework is missing, it is unclear what those details support. * Transitions and Topic Sentences: 15/20Don’t forget topic sentences at the start of every major point. They need to provide a transition, a connection to the thesis, and the topic/point of the paragraph/section. Therefore, when you start discussing atmosphere something like â€Å"Another reason why the party was so much fun was the atmosphere† would have worked. * A conclusion that reinforces the focus and dominant ideas in the text: 18/20 * Engaging Tone and Style:5/5 * Grammar, Punctuation, a nd Spelling: 8/10 * MLA Header and title: 5/5 GRADE: 80

“50 first dates” Movie Review Essay

50 first dates was a fun and a colorful movie, which brings the audience into curiosity. The movie is about a guy named Henry trying to build a romantic relationship with a girl named Lucy. Henry before was in to short-term attractions to the tourist. He was afraid of commitment because of what he went through in college. He would jump from one sexual attraction to another not think anything of it. While Lucy who had a mental disorder called Goldfield Syndrome, which made her lose her short-term memory. Really had no chose on being in a relationship because she wouldn’t remember the person the next day. That all changed the moment Henry first saw her in the cafe. From then on Henry made all the effort he could give just to win Lucy’s heart. Despite the syndrome Henry managed to let Lucy know how much he loves her through a video tape that he takes every single day. In this way, Lucy will know what happened to her and the tape is used to remind her what she did the past days. Visual arts was important to Henry because without it he could’ve not let Lucy remember what happened to her. Besides the story of Henry and Lucy in 50 first dates, visual arts plays a big role in my life. Not only because it makes life more colorful, but to think that art can express itself into a greater way that is through what a man can see. Not only do the visual arts provide pleasure and creative inspiration, but they also help foster dialogue and bring important issues to the public eye.

Market Competition Timing and Risks while entering or exiting a market Essay

Market Competition Timing and Risks while entering or exiting a market - Essay Example The researcher states that for example, Amazon.com started its business as an online bookshop but as gradually the demand for the grocery items had increased, Amazon.com adhering to that demand and started its first online grocery shop. As we see in the case of Monopoly where there are no competitors and therefore firms set a price to maximize profit and gain the first mover advantage. Whereas in a perfect competition there are no entry and exit barriers so the role of time in deciding the entrance or exit from the market is minimal and perfectly competitive firms are free to enter and exit an Industry and so in the case of Monopolistic competition in which there is a relative freedom of entry and exit out of industry but a difference between those two terms is that in Monopolistic competition the firms are not ‘perfectly’ mobile but they remain unrestricted by any government rules and regulations, start-up costs or any substantial barrier to entry which is the total opp osite of Oligopoly in which there are significant barriers to entry where time plays a major role in determining the entry and exit from the market. A firm has to evaluate several factors in order to determine the risks of new entrants and the reasons to exit a market which include â€Å"economies of scale, product differentiation, capital requirements, access to distribution channels, cost disadvantages independent of scale and government policies†... The term Economies of scale refers to increase the production of a commodity due to which the per-unit cost is of a commodity is reduced. This will create a risk for the new entrant firms in a sense that they would have to produce a larger quantity at a lower price. Economies of scale encourage the firms to exit the market that cannot produce the required quantity and it deters the smaller firms from entering into the market. These bigger firms forces the new entrants to either come in on a large scale or to accept a cost disadvantage (Porter, 1979). Product differentiation is a risk for entering into the market because it requires incurring expenditure and great deal of money to make the product differentiate among its competitors. Another type of risk is capital requirement where new entrants are required to invest larger amounts to compete efficiently in an industry; particularly if the capital is required for the research and development. The initial cost to operate can be so lar ge that it restricts all but the larger firms. The capital is not only required for fixed facilities but also for the inventories and absorbing start-up losses. While bigger firms have the financial resources to tap any industry but the huge capital investments in industries such as mineral extraction and computer manufacturing has major risks and limits the pool of entrants. Even the big firms do compete in this trio there is still no guarantee for success. Access to distribution channel is another type of risk in which a firm needs to obtain distribution for the channel and the distributors are not likely to deliver the product until they are paid good incentives and that will lead to profit reduction for the firm. For example, a new food product enters

Admission Eassy Essay Example | Topics and Well Written Essays - 250 words

Admission Eassy - Essay Example A specific industry that interests me a lot is enervation. I want to become a world leader in new enervation technologies and implementing them into a business environment. Completing an MBA degree will help a lot towards achieving my professional goals. The MBA program will improve my analytical abilities, market research capabilities, and quantitative reasoning. The enervation movement is important to me because the planet depends on the efforts of corporations in order to find ways to save energy and protect our environment. My professional experience includes working as a business analyst, instructional support technician, and salesman. These experiences have helped me improve my people skills. I have learned to work and deliver under pressure. My background in business at the undergraduate level and my working experiences make me an excellent candidate for the MBA program. Studying at the graduate level is going to be a very gratifying experience for me because I will get the ch ance to improve my knowledge base and meet a lot other students that have similar professional

Legalization Of Selling Human Organs Case Study

Legalization Of Selling Human Organs - Case Study Example Deaths that could be prevented by legalizing organ trade, pitting the merits of legalizing organ trade against the disadvantages of making it illegal. Legalizing the trade will save lives, activities of the black market will be erased, and organs will be available at cheaper prices for all. Universally, there is a problem caused by the high demand for transplants yet a shortage looms in terms of supply. Donations of organs by the deceased are affected by the legal system of countries and the socio-cultural factors. Even in developed countries where deceased organ donations are high, they fail to meet the growing demand. The use of live donors for kidneys and livers transplants is carried out, but the practice is termed illegal in many countries creating black markets for such scarce organs. Many arguments have been passed whether to legalize or not the trade, from medical, financial, legal and other points of view. All the countries are against legalizing organ trade except Iran. Other nations around the world have some laws when it comes to organ trade whether through legislation or outright ban and who can make donations. Presumed consent is being used by other countries to increase the supply of these vital organs which has been adopted by a country like France. Schemes have been developed by the government to compensate those who donate organs and coming up with legal initiatives to collect organs despite being involved in it being illegal. China is among the countries that have violated human rights in relation to organ trade where cases of kidnappings have been reported, strict and prohibitive laws and policies, have been passed to regulate the trade. (Kluger 42) In the world hot spot countries, The Times has identified where the black market of the organ trade takes place. They include South America in which illegal transplantation became an issue in Brazil.

Car insurance Research Proposal Example | Topics and Well Written Essays - 2750 words

Car insurance - Research Proposal Example Many purchasers simply sign on the bottom line without asking many questions or reading the policy. Let’s face it, insurance policies aren’t compelling reading material. They even make an attorney’s eyes glaze over. There are simple steps to take, however, to avoid being scammed. Most insurance scams begin by offering rates that seem ‘too good to be true.’ Guess what, they usually are. These low rates then suddenly jump up to higher than average sums a month or two into the policy’s duration. The insurance company blames some type of human or computer error and doesn’t honor the original quote. To lessen the chance of being scammed, confirm that the company is licensed by the state, as required by law. Ask questions about the coverage and obtain a copy of the policy. If the agent cannot sufficiently answer basic concerns, move on to the next company. Ask companies about their competitors, inquire to friends and neighbors regarding their insurance companies, never sign blank forms or pay in cash, many more people than you’d think are scammed after paying cash (â€Å"Insurance Scams† 2006). Choosing the best insurance company to fit the individual’s specific needs can be difficult and confusing. From national companies such as Allstate, Farmers, Geico, etc, to locally owned insurers, the choices are many but there are guidelines that help making an educated decision. Each state has a department that oversees insurance companies. If there are questions regarding licensing or if a person has issues with their insurance carrier, this state agency should be contacted for assistance. Prices vary widely among different insurance companies. Shopping around takes little time and can save a person hundreds of dollars a year. Phoning different companies and researching prices on the internet is well worth the time spent. Experts suggest getting at least three quotes before deciding. Most state’s insurance

Journal of Korean film Bedevilled (2010) Essay Example | Topics and Well Written Essays - 500 words

Journal of Korean film Bedevilled (2010) - Essay Example Cruelty of people, gendered violence, city and rural ways of being is remained to be the central problems that are involved into the film. It is possible to highlight two basic figures in the film that develop a plot and action. These are considered to be women those names are Hae-won and Pong-nam (Cho, 139-140). They have different characters and different faiths, but they both are presupposed to cruelty to some extent. The first one is represented as a cold lady with a severe and even brutal character. She works in a bank, lives in a big city, but is tired from all of this. She is used to behave impertinent and rude with all people around her. The moment that she becomes a witness of a crime and does nothing for the help of unfortunate woman proves the indifference and cruelty of her soul. Even when Hae-won’s old friend asks for the help she refuses despite the fact that she has been willing to provide it. The second woman represents the images of victim and murderer. This woman lives in a rural landscape and suffers from sexploitation and other bullying from people around her. Moreover, that is considered to be her husband, brothers and old women. Her soul is full of pain and infliction. Still, the patience of Pong-nam comes to an end when she loses her daughter and gets a refusal to save her from this hell. Since this moment Pong-nam becomes a murder. The thirst for revenge seizes this woman and she starts to requite for all pain that has been inflicted to her. In addition, it is relevant to admit the contrast between the settings that are represented in the film. The plot of â€Å"Bedevilled† develops in a huge city Seoul and rural place Moodo. Through these images it is possible to parallel civilized society and uncivilized one. City is viewed as a place where people can earn a lot of money and live better, while countryside is represented as a terrible and awful

Looking at organizational behaviours such as managment objectives, Assignment

Looking at organizational behaviours such as managment objectives, culture, knowledge about how people- as induviduals and as groups- act within organizations - Assignment Example The easiest probable approach is to promote the common interest of the group first thus, to gather altogether the efforts and interest of each unit and channel it towards the achievement of that goal. This is primarily the foundation of the aspect of organizational management, which is to maintain the necessary values inside the organization’s environment for the effectiveness and efficiency of the member’s efforts (Robinson, 2000). To do this, the management must be able to lead its member towards the tasks and responsibilities and be able to relate to the needs of each of its units. It is through this approach that the management is able to transcend the individuality barriers and diversity environment inside the organization for their productivity towards the common goal. (Sims 2002) On a personal reflection as a member of an actual organization management committee, there are several important concepts and terminologies that one must intricately understand to function effectively as an organizational manager. Most of these key concepts include the values that are important for the functions and operations of the organization and the issues that must be thoroughly addressed inside the organization (Robinson 2000). These important concepts are organizational behavior, organizational culture, diversity, communication, business ethics, and change management. First among the list is the task of fostering organizational behavior within the group particularly the necessary values and idealism that each individual member must possess. In this aspect, the management promotes the ideal behavior that is important for the group for it to function effectively towards the common goal (Robinson 2000). Indeed, the management must primarily establish the concepts of professionalism and teamwork within its member to enhance their productivity as a group. In this aspect, the

Leveraging IT for Business Assignment Example | Topics and Well Written Essays - 2500 words

Leveraging IT for Business - Assignment Example The benefits of offshoring are numerous to the company that engages in it. These include the reduction of the cost of doing business. Businesses have been able to reduce costs especially on the salaries that it pays out as well as other benefits. This is of benefit to the organization as it enables the organization to continue to function without unnecessary expense added to it (Click and Duening 2005). This is because most of the outsourcing destinations like China, India and other countries offer cheaper labour to these companies that outsource to them. Another benefit of outsourcing is the competitive advantage that it gives to those companies that use it. This is gained both in the local as well as in the international scene. This is due to the lower cost of business operations and the proximity to the available market for the finished goods. On the other hand, the difficulties of outsourcing a business are also present and must be put into consideration. These include the propor tionality of the projects availed and the provider of the BPO to fulfil the obligations. As the size of the provider goes up, so is the risk. At the same time, there is the matter of trust between the provider and recipient. The people or companies that are the recipients of the services that are being outsourced may be unknown. This means that it is a testing venture when a company, for example, far away, Australia decides to entrust its business to a little-known group like in India. The end result may be a poor show of the BPO which may be a great threat to the survival of the company. Another challenge to outsourcing is that it has the capacity to cause brain drain. According to unions within Australia, the outsourcing has driven a number of nationals from Australia to other countries in search of better terms of employment (Switzer 2006). This is because when companies outsource, they reduce the number of local jobs that they have. This is nature of unemployment that drives the job seekers elsewhere to try and survive. Outsourcings will, therefore, cost the country a lot of its highly productive labour.  

Principles of Distillation Essay Example for Free

Principles of Distillation Essay What is distillation? Simply, distillation is the process in which a liquid is vaporized (turned to steam), recondensed (turned back into a liquid) and collected in a container. Nature uses a form of distillation to turn salt water (seawater) into fresh water (rain). Why do you use distillation to recycle waste solvents? Solvent-based waste contains volatile material (solvents) and non-volatile material (contaminants like paint, ink, grease, fiberglass, etc.). Many of the non-volatile contaminates are dissolved in the solvent (like salt dissolved in salt water) and cannot be filtered-out. Distillation is an ideal way to separate the two. Why is distillation an ideal way to separate the two? During the distillation process, the solvent-based waste is heated until it reaches the boiling point. It then evaporates (vaporizes) and passes through the condenser where heat is removed from the vapor and it turns back into a cool, clean reusable liquid (same process that causes dew to form). Fortunately, contaminates are typically not volatile (easily vaporized) and stay behind in the distillation tank. You say contaminates are typically not volatile, does this mean some are? Occasionally there are cases where a potential customer wishes to separate a volatile solvent from another volatile material. This is not the typical customer. Some cases include customers using an alcohol to remove water from parts to dry them or where they have solvent mixtures due to poor house keeping practices (they lump all waste solvents into one drum from different operations like painting and parts cleaning). To separate one volatile from another effectively requires fractional distillation; our process uses simple distillation. What are the differences between simple distillation and fractional distillation? Simply stated, in simple distillation, what you put in is what you get back, but it is free of non-volatile materials (it is clean!). Fractional distillation is much more complicated (and expensive). It is the base process where crude oil is turned into the many items that come from oil. Fractional distillation is not required for virtually all solvent recycling applica tions. What is vacuum distillation? Vacuum distillation is the distillation of a liquid under reduced pressure. The atmospheric pressure in the distillation tank is reduced making it possible to boil the liquid at a lower temperature. Liquids boil at lower temperatures under reduced pressure (the inverse is that a liquid boils at a higher temperature under pressure, which is why they use a pressure cap on an automobile radiator to increase the boiling point of the engine coolant to prevent boil-over). Why do you use vacuum distillation? Vacuum distillation is used to safely recover higher boiling point solvents. We limit the maximum temperature of the distillation unit’s heater. There is a temperature at which a flammable or combustible material can ignite by temperature only, this is called the autoignition temperature (this is discussed later). Some solvents boil at temperatures that exceed the temperature that the distillation heater can reach (392 º Fahrenheit). Vacuum distill ation lowers the boiling point to allow recovery within the heaters maximum setting. When do you use vacuum distillation? It is used to safely recover solvents with boiling points over 300 º Fahrenheit. Vacuum distillation should not be used on solvents with boiling points below 200 º Fahrenheit. If the maximum heater setting is 392 º Fahrenheit, why do I need to use vacuum distillation for solvents with boiling points over 300 º Fahrenheit, don’t you mean solvents with boiling points over 392 º Fahrenheit? No! When boiling a liquid, two factors come in to play. One is the requirement to have a â€Å"driving force† to force the liquid to boil and vaporize. This â€Å"driving force† is in the form of extra temperature to allow the solvent to develop a good rolling boil. The other factor is the role of the non-volatile residue. As you boil off solvent and the remaining mixture in the distillation tank becomes more concentrated in the nonvolatile material, the vapor pressure drops (Raoult’s Law) and most important, the boiling point goes up! So bottom line is that you need 50 to 100 degrees of extra temperature to do a good job of boiling the waste solvent. Also, the concentrated non-volatile material acts as an insulator towards the end of the process as it becomes more and more concentrated. So, as the percentage of non-volatiles in the contaminated solvent increases, the required heat to completely distill the mixture also increases. Sometimes solvents that have boiling points of 318 ºF (Xylene) may not require a vacuum if they are not highly contaminated but almost definitely would if the solid content was greater than, lets say 10%. Pulling a vacuum on such a mixture will reduce its boiling point and the overall time to process it. How is the vacuum created? The vacuum is generated using our JetVac technology. A stainless steel reservoir is primed once with clean solvent. A small stainless steel pump is immersed in the liquid and is attached to an explosionproof electric motor. When the motor is started, clean solvent is drawn into the pump and forced through a metal tube known as an aspirator. The aspirator looks like an open piece of pipe with a small orifice (hole) on one side. As the high velocity fluid is pumped across the face of the orifice, it creates suction (like a venturi on a carburetor). Air is pulled through the venturi from the distillation system and passes through a vent.

Sociological Imagination Essay Example for Free

Sociological Imagination Essay The blackboard website will be unavailable between 7PM to midnight on June 29th for maintenance, so please make sure you upload it before 7 PM. Do not wait till last minute. Late assignments will result point deduction or even a zero essay grade. Format: Please submit an electronic word file named â€Å"your full name essay 1†, such as â€Å"JohnSmithessay1†, through blackboard on time. This essay should be 3-4 pages in total, double spaced, 11 point font. Do not directly copy and paste your assignment on blackboard! Choose to attach your assignment word file. Late assignments are not going to be accepted. The sociological imagination enables individuals to see the intimate relationship between the events of history as they occur in human societies and the events of an individuals or familys biography. wrote C. Wright Mills. In this assignment, you are to write up an Essay explaining the connections between your family biography and historical events over the past 50 years. Choose one family members of yours to focus on, such as your grandparents, you parents, your brothers and sisters, or you. Reflect on his or her life and think about how his/her life trajectory is intertwined with the historical changes in the country that you are from. The purpose of this assignment is to for you to apply the sociological imagination to analyze the profound influence that historical and societal contexts have on lives of individuals. Please make sure that you fulfill the following requirements: Clearly state what the personal events are. Explain how these personal events in your family are related to or affected by some of the historical events you listed. Explain in your own words what the sociological imagination is and whether/how it has helped you to better understand the life experiences of your family members. You can refer to the first assigned reading to answer these questions. Before you start your essay, you can do the following exercise on a piece of paper. Please do not include the time line drawing in your essay! It is just used for you to better conceptualize your essay. Draw a time line that begins in the 1960 and ends at the 2013. Above the line you are to identify in chronological order three significant events and/or transitions in the life of you or your family members (such events or transitions are like births, graduations, marriages, divorces, employment changes, income changes, geographic mobility, employment changes, or other changes you can think of). Next, think about the historical and social contexts underlying this particular individual’s life trajectory. What historical or societal events have affected his/her path or life? What historical or societal factors have influenced the important decisions he/she made in his/her life? Below the line identify in chronological order some of these important historical events. Write down the historical events and the time period it occurred or lasted. Such events in the United States include, are not limited to, World War II, the Cold War, the Korean War, the Civil Rights and Womens movements, the Vietnam War, the recession of the 1980s, and etc. Please do not be limited by the events I list here. You are free to choose some historical events that are less well known (such as the development of colon technology, tea party movement and etc.) but you think are influential in your life or the life of the family member that you chose. After you have decided which family member and life events to focus on, write an essay on the relationships between these personal events and some the important historical events in your country. Please note: I am not asking you to write what you or your family were thinking or doing on the day of 911 or the inauguration day of president Obama. You are supposed to write about how these historical events substantially shaped the life trajectory of the particular individual you chose. Your essay will be graded based on how well you answered each question and the overall quality of your assignment. I strongly recommend you read the grading rubric in the appendix carefully before you start. Please organize your thoughts and arguments, present them in a logical manner and explain them in detail. Please proof read papers for typographical and grammatical errors. Appendix 1: excerpts of other students assignments as example The following are some examples from other students assignments. Please learn from them how to apply the sociological perspective to your own life events but do not be constrained by them. (1) During World War II my family underwent some great changes. My grandmother took a second job, working in the woolen mills making army blankets. My grandfather joined the marines and moved his whole family from Ohio to California It was during this time that my grandparents divorced. Divorces are higher during any period of dramatic economic change. Although Im sure my grandparents blamed themselves, their divorce was a product of the economy and society. The same theory holds true for my parents. When they divorced, they blamed themselves, wondering what each had done wrong, as I did. When I look at what was happening in the economy, the similarities [with my grandparents] are easy to see. The nation- wide divorce rate was up dramatically and the economy was beginning to take a terrible turn for the worse. (2)When people ask me why I enrolled in college a year ago, I usually answered that I enrolled because I wanted to. I realize now that my answer cannot be quite that simple. Because my family doctor believed that the pill was finally proven safe in 1963, I was able to plan my family. In doing so, my son and daughter are nearly raised and I am still young enough to pursue a second career. More than any other factor, though, the womens movement probably was the greatest influence on my decision. The successes of the movement in social equality have given me the necessary courage and confidence to attempt to be more than a mere shadow of my husbands social position. Appendix 2: grading rubric Sociological Understanding (40%) The essay should apply key sociological concepts, ideas, theories learned in class correctly and properly to analyze related topics. Assertions in the essay must be supported by evidence (from texts or from data) that is logically related to the thesis. Coverage (30%) The essay must be clearly based on readings and topics related to the course. Essays that are simple summaries of sources are adequate, but will not get the highest grades. The essay should answer all the required questions in the essay guideline. If you fail to answer any questions, some points will be deducted. However, you should organize the essay in a way that it flows smoothly. Do not just list your answers to each question. Originality (10%) The essay should be original. Originality does not mean that you must be the first to think or write something, but that you take different sources and write about them using your point of view. Originality is entailed in taking your sources and forging them into an essay in your voice. Summarizing sources will be adequate, but not very original. Papers written by you and previously submitted to other courses are not original for this course. Such recycled papers will get a failing grade. Copying directly from internet without citing properly is considered plagiarism and will result in a failing grade. What is plagiarism? Writing Quality (10%) Words and constructions should be chosen with care. Statements should be direct and clear.w The essay should contain no errors of sentence structure, spelling, word choice, or punctuation. If you have difficulty writing or English is your second language you should tell me at the beginning of the semester. Im not a writing teacher, but I will do what I can to help you become a better writer. You should also seek help at the Writing Center. Every paper must have a title and the authors name, either at the top of the first page or on a separate title page. All citations and references must be in ASA, APA or MLA format. The general tone of the essay should be academic and professional. Good writing often sounds like well-organized thoughtful conversation. I do not want you to imitate the turgid academic writing found in some sociology journals. I want you to write with a level of sophistication appropriate for well-educated college students.

Biomarkers for Alzheimer’s Disease Progression

Biomarkers for Alzheimer’s Disease Progression Alzheimer’s disease is slowly progressive and irreversible brain disease which is one of the most common cause of dementia [1]. In AD patients not only suffer from cognitive but also motor and sensory loss [2]. Although the mechanism of AD is not well understood still AD pathology is characterized by extra cellular amyloid-ÃŽ ² deposits and interacellular neurfibril tangles formation of hyperphosphorylation of tau protein. Being irreversible and neurological damaging disease, its very important to detect and diagonse at earlier or at some controlable time point. Some useful AD diagonstic biomarkers are required for this purpose. These biomarkers should also fullful the criteria of usefulness for AD detection. Biomarkers should become abnormal with the progression of disease in other words they should be dynamic and correlate with clinical symptom and severity of disease [3]. Recent research on use of specific AD biomarker for disease staging in vivo shows that AÃŽ ² dynamically correlates with disease at different stages of disease progression[4] [5]. But AÃŽ ² level varies in patients. Which suggests, through process of AÃŽ ² production starts earlier but AÃŽ ² as a biomarker only is not relibale, therefore alternative biomarker must be found along with AÃŽ ² generation process. Figure1. Biomakers and AD early detection Source; Modified from Ingelsson, M et al 2004. [4] AÃŽ ² can be produced through proteolytic processing of APP (amyloid precursor protein), which takes central position in AD pathogenesis. APP is single-pass transmembrane protein with larger ectodomain. Although the physiological functions of APP are not well known but has neuroprotective function and positive effect on cell growth [6]. APP is mainly produced in neurons and rapidly metabolized by secretase enzymes through alternative splicing by two pathways [7] [8]. Nonamyloidogenic processing of APP involving two secretases ÃŽ ±-secretase and ÃŽ ³-secretase while in amyloidogenic processing ÃŽ ²-secretase (identified as transmembrane aspartase protease BACE1) and ÃŽ ³-secretase are involved. Product generated during both processings have soluble ectodomain (sAPP ÃŽ ± and sAPP ÃŽ ²) respectively along with identical product called AICD (intracellular C-terminal fregmenets)[9]. More importantly amyloidogenic processing generates AÃŽ ², a sequence contained by sAPP ÃŽ ² part. In brain APP processing generates mainly AÃŽ ²40 and AÃŽ ²42 based on 40 and 42 amino acids residues depending on secretases ( see secretase table 1) through alternative splicings [10]. Along with regulatory subunits of ÃŽ ³-secretase complex, catalytic subunits presenilin1 (PS1) and presenilin 2 ( PS2) are involved mainly in deciding the length of these toxic form of AÃŽ ². These toxic forms of AÃŽ ² can aggregate and form plauqe that has more toxic effect [11]. With the progression of AD, symptoms also spread along with it depending on the vlunerability of different party of nervous system. More vlunerable areas are suppose to be effected earlier to others, the reason AD smptoms appear in different regions in a sequential order and consistency, although meachnism is poorly understood. Out of these early symtoms, one is olfactory impairement [12], which suggest olfactory system is one of the early vlunerable region during AD progression. Therefore finding the correlation between early phenomen of APP processing and one of ther earlier vlunerable area of nervous system might lead to valueable insights. This research has focused on APP processing in peripheral structures, the olfactory epithelium(OE), as well as CNS structures responsible for processing of incoming olfactory signals such as olfactory bulb(OB). The present study found unique APP processing in OE that has significance in providing not only possible biomarkers (including 25kDa, 55kDa and 80kDa) that can be used for screening and detection of AD before plaque formation but also for treatment purpose. Additionally, PS2 increased level was found in OE that possibly involved in unique APP processing and might also be crucial for understanding the ÃŽ ³-secretase role and controlling AD through ÃŽ ³-secretase as a therapeutic target. Table 1. Secretases responsible for APP processing. MATERIAL AND METHODS MATERIAL AND METHODS 1.1. Animal 1.1 .1. Transgenic Alzheimer’s disease model Tg2576 mice In this study, heterozygous Tg2576 mice were used, which express a human amyloid-ÃŽ ² precursor protein (APP) variant linked to Alzheimer’ disease, as developed and described previously [21].Age-matched non-transgenic littermates were served as wild-type control. All animal experiments were approved and conducted in accordance with guidelines of Ethic Committee of Seoul National University DGIST. Transgenic Alzheimer’s disease model Tg6799 mice Another AD model used in this study was Tg6799 mice, which expresses human amyloid precursor protein (APP) with three familial Alzheimer’s disease point mutations and two human presenilin1 mutations thus also known as 5x FAD mice. Both of these mutation types mainly contribute to increased production of AÃŽ ²42 [22]. Age-matched non-transgenic littermates were served as wild-type control. All animal experiments were approved and conducted in accordance with guidelines of Ethic Committee of Seoul National University DGIST. Table2. Transgenic models used for this study. Olfactory behavioral analysis Food buried, behavior test was performed to measure the mice smell ability to find a buried food pellet using olfactory cues as previously described [23] [24] [25] [26]. Olfactory test was taken blindly without revealing any genotypic information of mice before and during the experiment. Mice were deprived of food around 35 hours with free access to water. Before starting the experiment, adaptation time was provided 5~10 min to let them adapt in new prepared cage with new bedding material. This step was important for mice to be adapted to the new environment so that they would able to focus on finding food in a new environment. Similar cage were prepared with bedding material depth approximately 5 cm and food pellet was buried 2.5 cm below the surface. Latency or cut-off time ~15 min maximum was provided to each mice to find buried food. Latency time was recorded, as time between mouse inserted into the cage and grasping the food pellet, precisely using video tracking software and sy stem (EthoVision xt 9).